The 3 Most Common Types of Itch Allergy Itching

When your allergies recur, it feels very uncomfortable, right? Skin becomes itchy, reddish, swollen, or feels hot and sore. In addition, allergic reactions that often occur are sneezing, itchy and runny nose, or itchy and watery eyes. At times like this, of course you need drugs to deal with itchiness that makes you uncomfortable. To understand more about the choice of itching drugs due to allergies, consider the following review.

How it works for allergic itching drugs


Allergy itching medication works to relieve symptoms. When you eat or come in contact with allergens (allergens) that are actually harmless, histamine produced by the immune system will overreact. Histamine also commands the body to fight allergens. This is what causes allergic reactions or symptoms, namely the skin, nose and eyes feel itchy.

The 3 Most Common Types of Itch Allergy Itching


To relieve symptoms of allergies, itching drugs work to stop or limit the activity of histamine in the body. However, allergic itching drugs cannot be used to prevent allergic reactions or treat severe allergic reactions such as anaphylactics.

Antihistamine itching allergy medicine


If your allergy is recurrent, there are currently many medicines to treat allergic itching that can be purchased without a doctor's prescription. The following are the most common types of allergic itching drugs.


  • Cetirizine


Cetirizine is the generic name of a second generation antihistamine drug. This drug can fight the symptoms of allergies without causing drowsiness. Cetirizine is available as tablets, syrups and drops. Like most other second-generation antihistamines, this drug only needs to be taken once a day or according to the dosage recommended by your doctor or pharmacist.


  • Loratadine


This itchy drug is similar to cetirizine. Loratadine is also a second-generation antihistamine drug that does not cause drowsiness and is enough to be taken once a day.

Various studies have revealed that cetirizine and loratadine are equally effective in dealing with allergic symptoms, namely itching. However, for a faster antihistamine effect, cetirizine is still superior to loratadine.


  • Fexofenadine


Compared to other second-generation antihistamines, fexofenadine is the least of its side effects. According to various surveys conducted by experts, some people still feel sleepy after taking cetirizine or loratadine.

Meanwhile, fexofenadine at least causes drowsiness. However, according to a 2001 study, cetirizine and loratadine were still faster at stopping histamine.


  • Diphenhydramine


Unlike other itching drugs, diphenhydramine is a first generation antihistamine drug. So, this drug causes drowsiness and weakness. If you want to take this medicine, make sure you are not driving or operating the machine.

Corticosteroid allergy medicine


Corticosteroids or steroids are drugs to treat itching caused by inflammation due to allergies. There are three types of corticosteroid drugs, namely topical (topical), oral (drinking), and intravenous (injection).

Topical corticosteroids or topical creams work quickly to reduce inflammation and swelling in the skin that occurs due to allergic reactions. Mild corticosteroids such as hydrocortisone can be purchased without a prescription at a pharmacy.

If itching and rash does not improve after 7 days of applying a topical medication or getting worse, consult a doctor. Chances are the doctor will prescribe a steroid cream drug that is harder in the womb.

However, this drug must be used with caution, referring to the rules of use and the correct dosage according to rese. Because the side effects of these hard drugs can make skin become problematic as stretch marks arise.

In addition to topical corticosteroid drugs, there are also allergic drugs that are injected or given by mouth (systemic). This drug will generally be able to relieve itching and swelling in a short time. However, this medication is only prescribed by a doctor with a note that if itching is allergic to cause severe rashes, swelling, and also spread throughout your body.

Also, be aware that this systemic steroid drug is only used short-term. This drug can also have significant side effects and need to be monitored for use by a doctor. Some of the side effects that can occur include weight gain, bone thinning, cataracts, glaucoma, easy bruising and sleep disorders.


  • Calamine lotion


Calamine is an allergic itching drug that works by producing a cold sensation when applied to inflamed skin. You can get this itchy drug at a pharmacy or by prescription. Use this itch exactly as directed on the label or as prescribed by your doctor. Do not use more, less or longer amounts than the doctor recommends.

Before you apply topical calamine, wash the itchy skin with soap and water. After that, let the skin dry first. Shake the calamine bottle before use then rub it on the itchy skin. When applying calamine directly to the skin, rub it gently. Then, let it dry on your skin. You can also use cotton balls to apply this medicine to your skin. Wash your hands with soap and water after applying this allergy medicine.

Calamine lotion can leave thin residue on the skin when it dries. You can cover the itchy area and smear it with loose clothing, but calamine can stain the clothes you wear. Contact your doctor if symptoms do not improve after 7 days of itching allergy medicine used. Store at room temperature away from moisture and heat. Do not put it in the refrigerator.

When to see a doctor?


Generally after taking medication or applying the medicine to the skin, itchiness of allergic symptoms will improve. Rashes and itching will generally disappear within a week. Most skin allergies are not life-threatening. But in rare cases, a severe reaction called anaphylaxis may occur. Contact the hospital or 118 if you have allergic itching accompanied by the following symptoms:


  • Difficulty breathing
  • A feeling of tightness in the throat
  • Hoarseness or difficulty speaking
  • Swollen lips, tongue or throat
  • Nausea, stomach ache, or vomiting
  • Fast heartbeat
  • Anxiety or dizziness
  • Lost consciousness

The Most Trusted Original Viagra Store in Indonesia Serving 24 Hours Online

Viagra Sildenafil citrate is a generic drug in the form of blue tablets produced by the world's largest pharmaceutical company, Pfizer USA. Viagra blue pill acts as an anti erectile dysfunction supplement, such as premature ejaculation and impotence. Taking this powerful Viagra medicine from the United States can solve your sexual problems.

Trusted Original Viagra Store in Indonesia


Viagra is a powerful drug is the best invention by expert professors in the United States (US). They are the leading medical specialists in the field of male vitality. They created Viagra by working hard for years to get the best results and quality. Viagra aka blue pill is produced through research and has been clinically tested using modern methods and sophisticated medical devices.

Original Viagra Is More Effective Than Levitra And Cialis


Erectile dysfunction (ED) is a condition where male genitals are not able to function properly. The general term is IMPOTENCE.

Impotence is usually experienced by men aged 60 or over. However, nowadays, more and more men who are not old enough experience these symptoms. If left unchecked, this condition can cause impotence and even total impotence.

Viagra has been used by millions of people for more than 20 years. Meanwhile, it has established itself as the leading brand in the treatment of impotence that is most effective. Clinical studies show that Viagra is very safe to consume because it causes mild side effects on its users.

Since being commercialized in 1998, Sildenafil Viagra has managed to cure many people with erectile dysfunction disorders that are very frightening for men. This can be a solution for those of you who suffer from ED to try Viagra rather than levitra and cialis. Because viagra is better than other alternative medicines.

Viagra is a powerful drug specifically for men whose function is to treat premature ejaculation, and impotence. If you experience problems such as those mentioned above, please consume PT Pfizer's original viagra strong medicine correctly. Just by taking 1 Viagra tablet before sex, you will feel amazing benefits.

Aside from Being a Strong Medicine What Are the Benefits of Viagra? What are the side effects?


Besides functioning as a drug against erectile dysfunction, Sildenafil Viagra can also overcome heart problems and diabetes. cara menyimpan viagra also has side effects. Here are some of the benefits and side effects of Viagra that you should know about.


  • Treating Prostate Cancer


Although still in the early stages of research, Viagra can be used to treat prostate cancer and reduce tumor growth.

Professor Rakesh Kukreja from Virginia Commonwealth University and colleagues said that Viagra or in medical terms known as sildenafil can improve anti-tumor properties in prostate cancer. While at the same time reducing damage to the heart.


  • Fertilize Plants


Not only treat impotence in men. According to the results of research conducted by Israel and Australia, Viagra, which is dissolved in muddy water, will make plants more fertile and fresh.


  • Improve the health of premature babies


In its report on Drugs.com, Viagra is also used in babies born prematurely or who have abnormal growths in the uterus.

The goal is to increase blood in the uterus and placenta, so that babies who are still in the womb can continue to develop normally. Viagra can increase the chances of a premature baby's life. This is because Viagra contains nitric acid which is beneficial for the baby's growth.


  • Reducing lung disease


Besides being able to overcome heart problems and erectile dysfunction, it turns out the ingredients in Viagra can help sufferers of severe lung disease. Severe lung disease causes the lungs to thicken or stiffen, making it difficult for people to breathe. The research team found that after consuming Sildenafil Viagra, they could breathe better.

What Happens When You Drink Original Viagra?


Erectile dysfunction is a fairly common problem in men. One way to overcome this problem in bed is to drink Viagra. In terms of benefits, you surely already know the magic of this blue pill. But what about the reaction and how it works? A study conducted by Superdrug revealed the work phase of Viagra in minutes to a day after drinking.


  • First 12 minutes.


The body absorbs Viagra quickly, and some men will feel the effect that fast, which is experiencing an erection.


  • 27 minutes.


If a man hasn't experienced an erection in the first 12 minutes, it may take up to half an hour. According to the researchers, the average response time of Viagra is 27 minutes.


  • 24 hours.


After one day, the Sildenafil effect will disappear. Almost all traces of the drug disappear from the bloodstream, so does the sex drive.

Facts About Original Viagra Blue Pills



  1. Viagra is produced by a trusted pharmaceutical company, PFIZER INC.
  2. Viagra was originally designed for hypertension and angina (seated wind).
  3. Viagra's main competitors are Cialis (tadalafil) and Levitra (vardenafil).
  4. Viagra tablets are blue and diamond-shaped. Until now famous for the name of the blue pill
  5. Some athletes take the blue pill to be more confident when appearing on the field.
  6. Like other ED drugs, Viagra works by inhibiting the enzyme phosphodiesterase type 5 (PDE5).


Dosage and How to Drink Genuine Viagra that is Good and Right



  • The maximum dose in 1 x 24 hours is 1 tablet of 100 mg should not be more. Take it as directed by your doctor or pharmacist.
  • Drink about 30 minutes to 1 hour before appearing. The powerful Viagra drug is most effective when taken within this time span, because this blue pill requires a little time to react and stimulate an erection.
  • We recommend that you eat low-fat foods first so that the maximum reaction. Avoid high-fat foods like red meat and french fries, because eating high-fat foods can inhibit Viagra's reaction.


Where to Buy Original Viagra?


Be sure to buy original Viagra only at trusted pharmacies. Because Viagra that we sell really has quality number 1. If you want to buy drugs for impotence, be more careful and attentive, so you are not fooled by fake drugs. Because fake Viagra medicine will harm your health, especially in your vital organs. Click here to find out the characteristics or characteristics of authentic Viagra. For information on purchasing and consulting, please click here

Choice of Allergy Medication Itching You Can Try

Itching can be caused by a variety of things, including allergies. Allergy itching medication is usually in the form of hypo-allergenic or antihistamine drugs. In addition, there are also other types of allergic itching drugs with different ways of working.

Choice of Allergy Medication Itching You Can Try


Allergy is the body's immune system response to certain substances called allergens. In people who do not have allergies, allergen exposure will not cause a reaction. But when allergic sufferers are exposed to allergens, the immune system will overreact and release histamine. Histamine is released which will cause various allergic symptoms, including itching.

Various Choice of Itching Allergy Medication


When experiencing itching due to allergies, you can overcome it by bathing or compressing the skin using cold water. Of course you also need to stop contact with allergens as soon as possible.

If the itching does not subside, you may need an allergic itch. The following are some choices for allergic itching medication that can be given by a doctor:


  • Topical corticosteroids (topical)


One type is hydrocortisone. Hydrocortisone is a type of mild corticosteroid that can deal with itching due to allergies. This drug is available as an ointment. In addition to relieving itching, hydrocortisone ointment can also relieve swelling and redness that arises due to allergic or inflammatory reactions.

Before using this medicine, you need to do a doctor's examination first, to determine the cause of the itching that you experience.


  • Calamine ointment


Calamine ointment is made from a mixture of zinc oxide and various other ingredients. This ointment is commonly used to relieve itching due to mild allergic reactions.

How to use it, apply the ointment to the area of ​​itchy skin according to the instructions for use listed on the product packaging. However, avoid applying ointment to the eye, mouth, nose and genitals.


  • Antihistamines


Antihistamine-containing drugs can be used to relieve allergic itching. This is because antihistamines inhibit the production of histamine which is a trigger for allergic reactions that cause itching.

In addition to relieving itching, antihistamine drugs can also relieve other allergic reactions, such as allergic rhinitis and allergic conjunctivitis. This drug is available in tablets, capsules and syrup.

The use of antihistamines must be preceded by a doctor's examination, to match conditions and indications. Be careful when using this drug, because some types of antihistamines can cause drowsiness.


  • Oral and injection corticosteroids


Apart from being in the form of ointments, corticosteroid drugs are also available in tablet and injection form. Corticosteroids work by reducing inflammation due to allergic reactions that can cause itching.

You need to use this medicine according to the advice and instructions from your doctor. The reason, corticosterid drugs should not be used if the cause of itching on the skin is an infection or injury.

Several types of allergic itch medicines described above can be an option to relieve itching. However, you are still advised to do a doctor's examination so that the drug chosen is right and safe.

How to Overcome Allergies with Cetirizine and Loratadine

Hi, are there any friends who are allergic? Or have family and friends who are allergic to certain objects. Hmm, although it looks simple, it turns out that allergies also need to be dealt with correctly. I have a relative who has a severe allergy.

This brother used to be allergic to seafood. Every time he forced himself to try seafood like shrimp, he had to pay with a total rest of about two days. Not only symptoms of redness and itching, the body also became hot. Well, since this allergy is very close to our daily lives, there's nothing wrong with friends, we equip ourselves with a little knowledge about allergies.

Come Know Allergies


In general, allergy is a reaction of the immune system to foreign objects that are considered dangerous. Note friends, this is only considered, not necessarily also foreign objects are dangerous.

This reaction from the body's immunity occurs in objects or substances that enter the body or even just touch it. For example, allergic to insect bites, dust, drugs, certain foods, animal hair, and pollen. Besides cigarette smoke can also cause allergies you know.

How to Overcome Allergies with Cetirizine and Loratadine


People who have allergies will usually react to allergens commonly called allergens. The reaction for each allergen is different, depending on the level of resistance to the allergen. There are mild and those that are severe. In mild allergies reactions such as sneezing, shortness of breath, skin rashes, runny nose, coughing, itching and watery eyes. At a later stage allergies can cause swelling in parts of the body that come in contact with allergens.

How do you deal with allergies?


Because allergies are the body's reaction to certain objects, the easiest way to overcome them is to avoid contact with allergens that can trigger the body's reaction. However, this method is certainly not easy, friend. Perhaps to avoid certain foods can be done. However, to avoid dusty spaces, to meet suddenly with certain animals, hmmm it feels rather difficult. Unless we are always in a sterile environment and isolated from the outside world. 🙂

Then, what if allergy symptoms finally appear. When symptoms are seen, then the most effective way to overcome them is to immediately take an anti-allergic drug, commonly called an antihistamine.

Antihistamines themselves, apparently there are also two groups of friends. There are first generation antihistamines and there are also second generation. The difference between these two generations lies in the effects caused after consuming them. First generation antihistamines have a higher sleepy effect than the second generation. Hence, second generation antihistamines are more sought after in the market. On the market, antihistamines themselves are available in many brands. First generation antihistamines, for example, the CTM group and diphenhydramine. Whereas second generation antihistamines such as cetirizine and loratadine drugs.

Overcoming Allergies with Cetirizine and Loratadine


After we know more about what are allergies and symptoms, now let's friends know more about drugs to deal with the symptoms. As previously explained, there are two second-generation antihistamines that friends can use to relieve allergies.


  • Cetirizine


An antihistamine that has a mild drowsiness effect. The way cetirizine works by inhibiting the performance of histamine compounds produced by the body that cause allergic symptoms. Cetirizine has the active ingredient Cetirizine Dihydrochloride which is more comfortable because it does not interfere with the patient's activities. Is to reduce the effects of sedation (drowsiness) and some are mild anti-inflammatory properties. Cetirizine can reduce the symptoms of major allergic rhinitis such as runny nose, sneezing, itchy nose, watery eyes. Can reduce allergic symptoms such as bumps more quickly. Safe given in the long run. Its use is enough once a day.


  • Loratadine


Long-acting tricyclic antihistamines, Does not cause drowsiness or sedation. Reduces symptoms related to allergic rhinitis such as sneezing, runny nose, and itchy nose, and burning sensation in the eyes. Reducing the symptoms and signs of chronic urticaria and other allergic dermatological diseases. Like cetirizine, loratadine can be taken once a day only when there are allergic symptoms that appear.

Between these two drugs, which one is better? What is the difference between the two? If the question is which is better, of course it is tailored to the needs of each person. To be sure, both of these drugs are drugs that are prescribed so their use must be careful. Must follow the usage instructions stated on the package. Although both are useful in dealing with allergic symptoms and include second generation antihistamines, there are some differences from cetirizine and loratadine.

Here are the differences between cetirizine and loratadine



  1. Cetirizine can reduce allergic rhinitis symptoms greater than loratadine.
  2. The rate of reduction of urticaria symptoms in cetirizine is higher than loratadine. In cetirizine redness of red bumps reaches 95 percent while with loratadine reaches 70 percent.
  3. Reduction of allergic symptoms in the form of reddish rash by using cetirizine reached 90 percent, while with loratadine reached 62 percent.
  4. Estimated reduction in effects after consuming cetirizine is faster than using loratadine. When using Loratadine takes 24 hours, then with cetirizine can be faster. For children 2-12 years, it is recommended to use Loratadine.


What about the side effects of using the antihistamine cetirizine and antihistamine drugs? As previously explained, these two allergy medicines are prescribed drugs. Therefore, friends need to be careful and peruse every instruction on the packaging. If the effects caused after consuming cetirizine or loratadine are quite disturbing, it is better for friends to immediately consult a doctor.

Cetirizine, for example, has the side effects of fatigue, palpitations, insomnia, restlessness, hyperactivity, vision problems and urination disorders. While Loratadine can cause headaches and dizziness as if fainting. Even so, everyone's reaction will of course be different to the use of this drug.

What about the use of cetirizine and loratadine when breastfeeding? Although it is very useful in dealing with allergic symptoms, the use of cetirizine and loratadine for nursing mothers and also pregnant women needs to be a serious concern.

During pregnancy and breastfeeding, mothers are usually prohibited from consuming certain drugs. Although it is not uncommon to find cases of mothers who have allergies while breastfeeding. Moreover, according to some studies loratadine and cetirizine can affect breast milk so that it can harm the baby.

Besides friends or relatives who have allergies whether breastfeeding or not, still have to tell the doctor or pharmacist when taking other drugs, before consuming these two types of antihistamines. The reason, the use of antihistamines also has contraindications to the content of several other drugs.

So how are friends. It turns out that when peeled, there are also many things we need to know about this allergy. And certainly like the wise words that are always delivered, prevention is better than cure.

So, if friends or relatives have allergic symptoms, the best thing to do is to avoid interactions with allergens that cause allergies. If you already have and produce new allergic symptoms, then you can take medicine. The choice can be cetirizine or loratadine, just tailored to the needs of each friend. And of course with the knowledge of your doctor or pharmacist. Also read a lot about health information blogs.

Rules for Using Methylprednisolone for Sore Throat

Methylprednisolone is a type of corticosteroid drug to reduce symptoms of swelling, pain, and allergic reactions. This drug can be used to treat inflammation in various diseases, such as eye diseases, ulcerative colitis, and rheumatism. In addition, doctors also prescribe methylprednisolone for strep throat. Methylprednisolone is available in various brands. This medicine must be used by a doctor's prescription. This is how to use methylprednisolone for strep throat.

Rules for using methylprednisolone for strep throat


Methylprednisolone is commonly prescribed by doctors in the form of tablets that are swallowed by mouth. Use methylprednisolone as directed by your doctor. The dose of methylprednisolone for strep throat generally ranges between 4-48 mg per day in one or two divided doses. Check the drug packaging label for proper dosage instructions.

The dose of methylprednisolone for strep throat can be different for each patient. The factors that determine the dose of methylprednisolone are the health condition to be treated, its severity, the patient's body response to the drug, and also body weight (especially for pediatric patients). For pediatric patients, doctors usually start in the lowest dose.

Rules for Using Methylprednisolone for Sore Throat


Take methylprednisolone with or without food. If you experience abdominal pain after taking medication, you should take this medicine with food or after meals, to reduce stomach irritation. The use of methylprednisolone for strep throat in the long term or exceeding the dose can increase the risk of adrenal gland disorders. Therefore, the dose must be according to doctor's orders. Increasing and reducing drug dosages also need to be done gradually to reduce side effects and prevent withdrawal symptoms.

You are not advised to use the drug methylprednisolone if you have a yeast infection anywhere in your body. Therefore, before using methylprednisolone, tell your doctor about all your medical conditions, and about all other medicines that you are currently taking. There are many other diseases that can be influenced by steroid use, and many other drugs that can affect the efficacy of this drug.

What are the methylprednisolone drug brands available in Indonesia


You can get methylprednisolone for strep throat or for other diseases, by getting a generic drug, or choosing the following brands available in Indonesia, including:


  • Advantan
  • Cormetison
  • Depo-Medrol
  • Fumethyl
  • Gamesolone
  • Glomeson
  • Hexilon
  • Introl
  • Lameson
  • Medrol
  • Mesol
  • Metrison
  • Prednox
  • Prolon 8
  • Rhemafar
  • Sanexon
  • Simdrol
  • Solu-Medrol
  • Sonicor 4
  • Tison
  • Toras
  • Tropidrol
  • Xilon
  • Yalone


What to do if you forget to take methylprednisolone for strep throat?


If you forget one dose of this medicine, take it as soon as possible. But when it is nearing the next dose, skip the missed dose and return to the usual dosage schedule. Do not double the dose at once.

Do not also stop taking drugs suddenly without the doctor's approval. Some conditions can become more severe, or you may experience "sakaw" (for example, feeling weak, losing weight, nausea, muscle aches, headaches, fatigue, dizziness) when this drug is suddenly stopped. Inform your doctor if your condition has not improved or has worsened.

Medrol Tablet: Benefits, Dosages & Side Effects

Medrol Tablet is a drug used as an allergy, immunosuppressant, anti-shock and anti-inflammatory drug. Medrol Tablets contain Methylprednisolone, which is a type of synthetic glucocorticoid steroid drug. The following is complete information on Medrol Tablet drugs that are accompanied by links with other drug brands with the same generic name.

factory : Pfizer
group : On medical prescription

the packaging, Medrol Tablet is marketed with the following packages:

Dos 10 x 10 tablets 4 mg
Dos 30 tablets 16 mg

the womb

Each Medrol Tablet drug package contains an active substance (generic name) as follows:

Methylprednisolone 4 mg / tablet
Methylprednisolone 16 mg / tablet

An overview of active substances (generic names)

Medrol Tablet


Methylprednisolone is a synthetic glucocorticoid steroid drug. This drug is a prednisolone derivative that is used as an anti-allergic, immunosuppressant, and anti-inflammatory agent. Methylprednisolone works by penetrating cell membranes to form a steroid-protein receptor complex. In the cell nucleus, this receptor-steroid protein complex will bind to chromatin DNA and stimulate mRNA transcription which is part of the process of protein synthesis. As an anti-inflammatory, this drug suppresses neutrophil migration, reduces the production of prostaglandins (compounds that function as inflammatory mediators), and causes capillary dilatation. This will reduce the body's response to inflammatory conditions (inflammation).

Indication


The usefulness of Medrol Tablet (methylprednisolone) is for the treatment of the following conditions:


  1. Like other glucocorticoids, Medrol Tablet (methylprednisolone) is used as an anti-inflammatory drug (inflammation), as an allergic drug, endocrine disease, haematological disorders, and nephrotic syndrome. (Recognize food allergies and how to overcome them).
  2. Medrol tablets for strep throat medications are also very commonly used. Generally used for the short term. Strep throat / bronchial or acute bronchitis occurs due to various respiratory diseases.
  3. Can also be used in the treatment of arthritis (rheumatism). (Complete Explanation of Joint Pain).
  4. In the treatment of autoimmune diseases, such as systemic lupus erythematosus in the acute period and long-term therapy, hemolytic anemia and erythoblastopenia.
  5. This drug is also used as a treatment for multiple sclerosis, nonpenetrating spinal cord injury, steven johnson syndrome, exfoliative dermatitis, psoriasis, acute and chronic eye inflammation, chronic and acute lymphocytic leukemia, chronic and acute lymphocytic leukemia, insufficient adrenal cortex, thrombocytopenia purpura in adults, and vestibular neuritis.
  6. Counter indication
  7. Do not use Medrol Tablet if you have a history of hypersentive / allergy medication methylprednisolone or other glucocorticoid medications.
  8. This drug is also contraindicated for people with tuberculosis (TB), diabetes mellitus, systemic fungal infections, herpes simplex disease, varicella, and severe osteoporosis sufferers.
  9. In addition, administration of live vaccines or weakened vaccines is also contraindicated for someone who is using immunosuppressive drugs such as Medrol Tablet (methylprednisolone). Exceptions to this rule are patients undergoing complete corticosteroid replacement therapy, for example, for addison's disease, which may follow standard immunization protocols.


Side Effects of Medrol Tablets


Here are some of the side effects of Medrol Tablet (methylprednisolone):


  • Side effects of Medrol Tablet (methylprednisolone) on short-term use such as fluid and sodium retention, hyperglycemia and glucose intolerance, hypokalemia, disorders of the digestive tract and ulceration, reversible depression of the hypothalamic-pituitary-adrenal (HPA) axis, and changes in mood such as euphoria mild, nervous, restless, depressed, delusional, hallucinatory, and violent behavior.
  • Effects of long-term use are all side effects on short-term use plus cushing syndrome (one feature: facial swelling), hirsutism or virilism, impotence, irregular menstruation, peptic ulcer disease, weight gain, congestive heart insufficiency, edema, hypertension, cataracts and increased eye intraocular pressure / glaucoma, myopathy, osteoporosis, impaired wound healing, impaired carbohydrate metabolism, muscle weakness, and vertebral compression fractures.
  • Long-term use of this drug also causes a decrease in the immune system making it more susceptible to fungal or viral infections.
  • The most serious side effect is that the adrenal glands stop producing cortisol naturally.


Attention

The following are things that patients should be aware of when using Medrol Tablet (methylprednisolone):


  • This medicine is used after eating or with food.
  • Do not stop using this drug suddenly because it can result in an addisonian crisis which can be fatal. To prevent this, doctors usually prescribe this drug by tapering dose (increased gradually, stopped gradually).
  • Systemic corticosteroids such as Medrol Tablet (methylprednisolone) are known to be excreted in breast milk. Because this drug can inhibit growth, interfere with endogenous corticosteroid production, or cause other undesirable effects, you should use Medrol Tablet (methylprednisolone) during breastfeeding to avoid.
  • Medrol Tablets drugs that can cause insomnia and mood disorders.
  • Avoid contact with measles and chickenpox sufferers, because users of Medrol Tablet (methylprednisolone) will experience a decrease in the immune system so that it is more easily infected.


Use of Medrol Tablet for pregnant women


The FDA (United States Food and Drug Administration) categorizes methylprednisolone in category C with the following explanation:

Research on animal reproduction has shown adverse effects on the fetus and there are no adequate and well-controlled studies in humans, but if the potential benefits can be guaranteed, the use of drugs in pregnant women can be carried out despite the enormous potential risk.
Although the results of studies in animals are not always equivalent to results in humans, the use of Medrol Tablets for pregnant women should be avoided. If it is not really needed or therapy with drugs or other means is still possible, you should not use this drug.

drug interactions


Medicines containing the active ingredient methylprednisolone interact with the following drugs:


  1. If given along with potassium-depleting agents (for example, amphotericin B, diuretics), you should be aware of the possibility of hypokalemia, cardiac enlargement and congestive heart failure.
  2. Macrolide antibiotics cause a significant decrease in methylprednisolone clearance thereby increasing the potential for side effects.
  3. Methylprednisolone inhibits the warfarin response, therefore, the coagulation index must be monitored regularly to maintain the desired anticoagulant effect.
  4. Methylprednisolone can increase blood glucose concentration, adjusting the dose of antidiabetic drugs may be needed.
  5. Methylprednisolone causes a decrease in the serum concentration of isoniazid.
  6. Cholestyramine can increase oral methylprednisolone clearance.
  7. Giving in conjunction with cyclosporine will increase the activity of both drugs. This increases the risk of seizures.
  8. Estrogen (including oral contraceptives) can reduce the hepatic metabolism of methylprednisolone, thereby increasing its effect.
  9. Drugs that induce cytochrome P450 3A4 (eg Barbiturates, Phenytoin, Carbamazepine, Rifampin), enzyme activity can increase corticosteroid metabolism so that the dose of Medrol Tablet (methylprednisolone) needs to be increased.
  10. Drugs that inhibit cytochrome P450 3A4 (for example, ketoconazole, macrolide antibiotics such as erythromycin and troleandomycin) have the potential to produce an increase in the concentration of methylprednisolone plasma.
  11. Ketoconazole significantly reduces methylprednisolone metabolism thereby increasing the risk of methylprednisolone side effects.
  12. Use with NSAIDs should be aware of the increased risk of gastrointestinal bleeding.


Medrol Tablet Dosage


The dosage of this drug is determined individually for each patient based on the benefits and tolerability of each patient. Medrol drug Tablet (methylprednisolone) is generally given at the following dosages:

Adults and children aged 12 years or more: 4-48 mg / day as a single dose or divided dose.
In the case of sclerosis: 160 mg / day for 1 week, followed by 64 mg / day for 1 month.
Children under 12 years old:
Initial dose: 0.4-1.6 mg / kg body weight / day. Not more than 80 mg / day. Maintenance: 2-8 mg / day. Note:

Increasing the dose and stopping the drug is done in stages, as prescribed by the doctor.

Related


Drug brands containing methylprednisolone
Drugs that include corticosteroids
Medications including glucocorticoids
In drug selection, the benefits obtained must be greater than the risks that the patient may experience. Therefore, the use of Medrol Tablet should be as recommended.